To connect the backend, frontend, and database in Python, follow these steps:

1. Choose a Backend Framework: Use Flask or Django for the backend. For simplicity, start with Flask.

2. Set Up the Database:

3. Select SQLite or MySQL.

4. Use an ORM like SQLAlchemy to interact with the database.

5. Configure the Backend:

6. Integrate Flask with your database using Flask-SQLAlchemy.

7. Create models for your database tables.

8. Develop API Endpoints:

9. Define routes in your Flask app to handle HTTP requests.

10. Implement database operations within these routes.

11. Build the Frontend:

12. Use JavaScript frameworks like React or Vue.js.

13. Make AJAX calls using Axios or Fetch API to communicate with the backend.

14. Handle CORS: If the frontend and backend are on different domains, use Flask-CORS to enable cross-origin requests.

15. State Management: Use Redux (for React) or Vuex (for Vue.js) to manage application state.

16. Testing:

17. Test API endpoints with tools like Postman.

18. Implement unit tests for both frontend and backend components.

19. Deployment:

20. Deploy the backend using Gunicorn and Nginx.

21. Host frontend files on a static server or CDN.

22. Database Deployment: For MySQL, set up a remote database instance and configure access permissions.

By following these steps, you can successfully integrate your Python backend with a frontend and database, creating a functional web application.